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This deficiency can result from conditions such as pernicious anemia, certain gastrointestinal disorders, or a diet low in animal products

When NF-kB translocates to the cell nucleus, it switches on the transcription of pro-inflammatory cytokines including TNF-alpha, IL-6, and IL-1-beta

The main localizations of angioedema attacks were facial oedema (50%) and abdominal pain (50%), then peripheral oedema (12%), laryngeal (12%) and tongue (12%) oedema

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